Publications

For a complete list, check out Google Scholar

68. George, Hannah; Steeves, Katherine L.; Mercer, Grace V.; Aghaei, Zahra; Schneider, Céline M.; Cahill, Lindsay S. (2022) Endothelial nitric oxide deficiency results in abnormal placental metabolism. Placenta. 128:36.

67. Aghaei, Zahra; Sled, John G.; Kingdom, John C.; Baschat, Ahmet A.; Helm, Paul A.; Jobst, Karl J.; Cahill, Lindsay S. (2022) Maternal exposure to polystyrene micro- and nanoplastics causes fetal growth restriction in mice. Environmental Science and Technology Letters. 9:426.

66. Schneider, Céline M.; Steeves, Katherine L.; Mercer, Grace V.; George, Hannah; Paranavitana, Leah; Simpson, Myrna J.; Simpson, André J.; Cahill, Lindsay S. (2022) Placental metabolite profiles in late gestation for healthy mice. Metabolomics. 18:10.

 

65. Aghaei, Zahra; Steeves, Katherine L.; Jobst, Karl J.; Cahill, Lindsay S. (2022) The impact of perfluoroalkyl substances on pregnancy, birth outcomes and offspring development: a review of data from mouse models. Biology of Reproduction. 106:397.

 

64. Tran, Vanessa; Weckman, Andrea; Crowley, Valerie; Cahill, Lindsay S.; Zhong, Kathleen; Cabrera, Ana; Elphinstone, Robyn; Pearce, Victoria; Madanitsa, Mwayiwawo; Kalilani-Phiri, Linda; Mwapasa, Victor; Khairallah, Carole; Conroy, Andrea; ter Kuile, Feiko O.; Sled, John G., Kain, Kevin C. (2021) The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy. EBioMedicine. 73:103683.

 

63. Rahman, Anum; DeYoung, Taylor; Cahill, Lindsay S.; Yee, Yohan; Debebe, Sarah K.; Botelho, Owen; Seed, Mike; Chaturvedi, Rajiv R.; Sled, John G. (2021) A surgically induced mouse model of hypoplastic left heart syndrome. Disease Models and Mechanisms. 14:dmm049077.

 

62. Cahill, Lindsay S.; Mercer, Grace V.; Jagota, Dakshita; Ravi Chandran, Anjana; Milligan, Natasha; Shinar, Shiri; Whitehead, Clare L.; Hobson, Sebastian R.; Serghides, Lena; Parks, W. Tony; Macgowan, Christopher K.; Kingdom, John C.; Sled, John G.; Baschat, Ahmet A. (2021) Doppler ultrasound of the fetal descending aorta: an objective tool to assess placental blood flow resistance in pregnancies with discordant umbilical arteries. Journal of Ultrasound in Medicine. 9999:1.

 

61. Saghian, Rojan; Cahill, Lindsay S.; Rahman, Anum; Steinman, Joe; Stortz, Greg; Kingdom, John; Macgowan, Christopher K.; Sled, John G. (2021) Interpretation of wave reflections in the umbilical arterial segment of the feto-placental circulation: computational modelling of the feto-placental arterial tree. IEEE Transactions on Biomedical Engineering. 68:3647-3658.

 

60. Cahill, Lindsay S.; Stortz, Greg; Ravi Chandran, Anjana; Milligan, Natasha; Shinar, Shiri; Whitehead, Clare L.; Hobson, Sebastian R.; Ayyathurai, Viji; Rahman, Anum; Saghian, Rojan; Jobst, Karl J.; McShane, Cyrethia; Block-Abraham, Dana; Seravalli, Viola; Laurie, Melissa; Millard, Sarah; Delp, Cassandra; Wolfson, Denise; Baschat, Ahmet A.; Murphy, Kellie E.; Serghides, Lena; Morgen, Eric; Macgowan, Christopher K.; Parks, W. Tony; Kingdom, John C.; Sled, John G. (2021) Wave reflections in the human umbilical artery measured by Doppler ultrasound as a novel predictor of placental pathology. EBioMedicine. 67:103326.

 

59. Mohan, Haneesha; Laurette, Evelyn Y.; Tejada, Oscar; Sanghvi, Tanvi; Leung, Kit-Yi; Cahill, Lindsay S.; Sled, John G.; Delgado-Olguin, Paul; Greene, Nicholas D.E.; Copp, Andrew J.; Serghides, Lena. (2021) In response to the Letter to the Editor by Romach et al. re. our publication “Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not supratherapeutic levels”. EBioMedicine. 66:103334.

 

58. Jagota, Dakshita; George, Hannah; Walker, Melissa; Ravi Chandran, Anjana; Milligan, Natasha; Shinar, Shiri; Whitehead, Clare L.; Hobson, Sebastian R.; Serghides, Lena; Parks, W. Tony; Baschat, Ahmet A.; Macgowan, Christopher K.; Sled, John G.; Kingdom, John C.; Cahill, Lindsay S. (2021) Sex differences in fetal Doppler parameters during gestation. Biology of Sex Differences. 12:26.

 

57. Chatterjee, Antara; Dorogin, Anna; Saghian, Rojan; Cahill, Lindsay S.; Sled, John G.; Lye, Stephen; Shynlova, Oksana. (2021) Combination of histochemical analyses and micro-MRI reveals regional changes of the murine cervix in preparation for labor. Scientific Reports. 11:4903.

 

56. Doroshenko, Ellinore R.; Drohomyrecky, Paulina C.; Gower, Annette; Whetstone, Heather; Cahill, Lindsay S.; Ganguly, Milan; Spring, Shoshana; Yi, Taeo Joon; Sled, John G.; Dunn, Shannon E. (2021) Peroxisome proliferator-activated receptor-δ deficiency in microglia results in exacerbated axonal injury and tissue loss in experimental autoimmune encephalomyelitis. Frontiers in Immunology. 12:570425.

 

55. Paranavitana, Leah; Walker, Melissa; Ravi Chandran, Anjana; Milligan, Natasha; Shinar, Shiri; Whitehead, Clare L.; Hobson, Sebastian R.; Serghides, Lena; Parks, W. Tony; Baschat, Ahmet A.; Macgowan, Christopher K.; Sled, John G.; Kingdom, John C.; Cahill, Lindsay S. (2021) Sex differences in uterine artery Doppler during gestation in pregnancies complicated by placental dysfunction. Biology of Sex Differences. 12:19.

 

54. Cahill, Lindsay S.; Shinar, Shiri; Whitehead, Clare L.; Hobson, Sebastian R.; Stortz, Greg; Ayyathurai, Viji; Ravi Chandran, Anjana; Rahman, Anum; Kingdom, John C.; Baschat, Ahmet; Murphy, Kellie E.; Serghides, Lena; Macgowan, Christopher K.; Sled, John G. (2021) Sex differences in modulation of feto-placental vascular response in growth-restricted mouse fetuses following betamethasone administration: comparisons with human fetuses. American Journal of Obstetrics and Gynaecology Maternal-Fetal Medicine. 3:100251.

 

53. Mohan, Haneesha; Guzman Lenis, Monica; Laurette, Evelyn Y.; Tejada, Oscar; Sanghvi, Tanvi; Leung, Kit-Yi; Cahill, Lindsay S.; Sled, John G.; Delgado-Olguin, Paul; Greene, Nicholas D.E.; Copp, Andrew J.; Serghides, Lena. (2021) Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels. EBioMedicine. 63:103167.

 

52. Cahill, Lindsay S.*; Stortz, Greg*; Ravi Chandran, Anjana; Milligan, Natasha; Shinar, Shiri; Whitehead, Clare L.; Hobson, Sebastian R.; Millard, Sarah; Macgowan, Christopher K.; Kingdom, John C.; Sled, John G.; Baschat, Ahmet A. (2021) Determination of fetal heart rate short term variation from umbilical artery Doppler waveforms. Ultrasound in Obstetrics and Gynecology. 57:70-74.

 

51. Stortz, Greg; Cahill, Lindsay S.; Ravi Chandran, Anjana; Baschat, Ahmet; Sled, John G.; Macgowan, Chris K. (2020) Quantification of wave reflection in the human umbilical artery from asynchronous Doppler ultrasound measurements. IEEE Transactions in Medical Imaging. 39:3749-3757.

 

50. Cahill, Lindsay S.; Cameron, Jessie M.; Winterburn, Julie; Macos, Patrick; Hoggarth, Johnathan; Dzamba, Misko; Brudno, Michael; Nutter, Lauryl M.J.; Sproule, Thomas J.; Burgess, Robert W.; Henkelman, R. Mark; Sled, John G. (2020) Structural variant in mitochondrial-associated gene (MRPL3) induces adult-onset neurodegeneration with memory impairment in the mouse. Journal of Neuroscience. 40:4576-4585.

 

49. Steinman, Joe; Cahill, Lindsay S.; Stortz, Greg; Macgowan, Christopher K.; Stefanovic, Bojana; Sled, John G. (2020) Non-invasive ultrasound detection of cerebrovascular changes in a mouse model of TBI. Journal of Neurotrauma. 37:2157-2168.

 

48. Debebe, Sarah K.; Cahill, Lindsay S.; Kingdom, John C.; Whitehead, Clare L.; Ravi Chandran, Anjana; Parks, W Tony; Serghides, Lena; Baschat, Ahmet; Macgowan, Christopher K.; Sled, John G. (2020) Wharton’s jelly area and its association with placental morphometry and pathology. Placenta. 94:34-38.

 

47. Ngai, Michelle; Weckman, Andrea M.; Erice, Clara; McDonald, Chloe R.; Cahill, Lindsay S.; Sled, John G.; Kain, Kevin C. (2020) Malaria in pregnancy and adverse birth outcomes: new mechanisms and therapeutic opportunities. Trends in Parasitology. 36:127-137.

 

46. Fouquet, Jérémie P.; Lebel, Réjean; Cahill, Lindsay S.; Sled, John G.; Tremblay, Luc; Lepage, Martin. Cerebrovascular MRI in the mouse without an exogenous contrast agent. (2020) Magnetic Resonance in Medicine. 84:405-415.

 

45. Cahill, Lindsay S.*; Zhang, Monan Angela*; Ragmalia, Valeria; Whetstone, Heather; Sabbagh, Melika Pahlevan; Yu, Tae Joon; Woo, Laura; Przybycien, Thomas S.; Moshkova, Marina; Zhao, Fei Linda; Rojas, Olga L.; Gomes, Josephine; Kurten, Stefanie; Gommerman, Jennifer L.; Sled, John G.; Dunn, Shannon E. (2019) Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis. Proceedings of the National Academy of Sciences. 116:22710-22720.

 

44. Cahill, Lindsay S.; Pilmeyer, J.; Yu, Lisa X.; Steinman, Joe; Hare, Gregory M.T.; Kassner, Andrea; Macgowan, Christopher K.; Sled, John G. (2019) Ultrasound detection of abnormal cerebrovascular morphology in a mouse model of sickle cell disease based on wave reflection. Ultrasound in Medicine & Biology. 45:3269-3278.

 

43. Steinman, Joe; Cahill, Lindsay S.; Koletar, Margaret M.; Stefanovic, Bojana; Sled, John G. (2019) Acute and chronic stage adaptations of vascular architecture and cerebral blood flow in a mouse model of TBI. NeuroImage. 202:116101.

42. Kay, Vanessa R.; Cahill, Lindsay S.; Hanif, Anas; Sled, John G.; Carmeliet, Peter; Tayade, Chandrakant; Croy, B. Anne. (2019) Adult Pgf-/- mice behaviour and neuroanatomy are altered by neonatal treatment with recombinant placental growth factor. Scientific Reports. 9:9285.  

41. Cahill, Lindsay S.; Whitehead, Clare L.; Hobson, Sebastian R.; Stortz, Greg; Kingdom, John C.; Baschat, Ahmet; Murphy, Kellie E.; Serghides, Lena; Macgowan, Christopher K.; Sled, John G. (2019) Effect of maternal betamethasone administration on feto-placental vascular resistance in the mouse. Biology of Reproduction. 101:823-831.

40. Sled, John G.; Stortz, Greg; Cahill, Lindsay S.; Milligan, Natasha; Ayyathurai, Viji; Serghides, Lena; Morgen, Eric; Seravalli, Viola; Delp Cassandra; McShane, Cyrethia; Baschat, Ahmet; Kingdom, John; Macgowan, Christopher K. (2019) Reflected hemodynamic waves influence the pattern of Doppler ultrasound waveforms along the umbilical arteries. American Journal of Physiology – Heart and Circulatory Physiology. 316:H1105-H1112.

39. Cahill, Lindsay S.; Zhou, Yu-Qing; Hoggarth, Johnathan; Yu, Lisa X.; Rahman, Anum; Stortz, Greg; Whitehead, Clare L.; Baschat, Ahmet; Kingdom, John C.; Macgowan, Christopher K.; Serghides, Lena; Sled, John G. (2019) Placental vascular abnormalities in the mouse alters umbilical artery wave reflections. American Journal of Physiology – Heart and Circulatory Physiology. 316:H664-H672.

38. Cahill, Lindsay S.; Hoggarth, Johnathan; Lerch, Jason P.; Seed, Mike; Macgowan, Christopher K.; Sled, John G. (2019) Fetal brain sparing in a mouse model of chronic maternal hypoxia. Journal of Cerebral Blood Flow and Metabolism. 39:1172-1184.

37. Kay, Vanessa*; Ratsep, Matthew*; Cahill, Lindsay S.; Hickman, Andrew; Zavan, Bruno; Newport, Margaret; Ellegood, Jacob; Laliberte, Christine; Reynolds, James; Carmeliet, Peter; Tayade, Chandrakant; Sled, John G.; Croy, B. Anne. (2018) Effects of placental growth factor deficiency on behaviour, neuroanatomy and cerebrovasculature of mice. Physiological Genomics. 50:862-875.

36. Yee, Yohan; Fernandes, Darren J.; French, Leon; Ellegood, Jacob; Cahill, Lindsay S.; Vousden, Dulcie A.; Spencer Noakes, Leigh; Scholz, Jan; van Eede, Matthijs C.; Nieman, Brian J.; Sled, John G.; Lerch, Jason P. (2018) Structural covariance of brain region volumes is associated with both structural connectivity and transcriptomic similarity. NeuroImage. 179:357-372.

35. Mohammadi, Hakimeh; Papp, Eszter; Cahill, Lindsay; Rennie, Monique; Banko, Nicole; Pinnaduwage, Lakmini; Lee, Janice; Kibschull, Mark; Dunk, Caroline; Sled, John G.; Serghides, Lena. (2018) HIV antiretroviral exposure in pregnancy induces detrimental placenta vascular changes that are rescued by progesterone supplementation. Scientific Reports. 8:6552.

34. Mistry, Nikhil; Mazer, C. David; Sled, John G.; Lazarus, Alan H.; Cahill, Lindsay S.; Solish, Max; Zhou, Yu-Qing; Romanova, Nadya; Hare, Alexander G.M.; Doctor, Allan; Fisher, Joseph A.; Brunt, Keith R.; Simpson, Jeremy A.; Hare, Gregory M.T. (2018) Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. 314:R611-R622.

33. McDonald, Chloe R.; Cahill, Lindsay S.; Gamble, Joel R.; Elphinstone, Robyn; Gazdzinski, Lisa M.; Zhong, Kathleen J.Y.; Philson, Adrienne C.; Madanitsa, Mwayiwawo; Mwapasa, Victor; ter Kuile, Feiko O.; Sled, John G.; Conroy, Andrea L.; Kain, Kevin C. (2018) Malaria in pregnancy alters L-arginine biogenesis in Malawian women and L-arginine supplementation improves birth outcomes in a pre-clinical model. Science Translational Medicine.10:eaan6007.

32. Cahill, Lindsay S.; Rennie, Monique Y.; Hoggarth Johnathan; Yu, Lisa X.; Rahman, Anum; Kingdom, John C.; Seed, Mike; Macgowan, Christopher K.; Sled, John G. (2018) Feto- and utero-placental vascular adaptations to chronic maternal hypoxia in the mouse. Journal of Physiology. 596.15:3285-3297.

31. Rennie, Monique Y.; Cahill, Lindsay S.; Adamson, S. Lee; Sled, John G. (2017) Arterio-venous fetoplacental vascular geometry and hemodynamics in the mouse placenta. Placenta. 58:46-51.

30. Rahman, Anum; Cahill, Lindsay S.; Zhou, Yu-Qing; Hoggarth, Johnathan; Rennie, Monique Y.; Seed, Mike; Macgowan, Chris K.; Kingdom, John C.; Adamson, S. Lee; Sled, John G. (2017) A mouse model of antepartum stillbirth. American Journal of Obstetrics and Gynecology. 217:e1-443.e11.

29. Chi, Lijun; Ahmed, Abdalla; Roy, Anna; Vuong, Sandra; Cahill, Lindsay S.; Caporiccio, Laura; Tarakhovsky, Alexander; Sled, John G.; Caniggia, Isabella; Wilson, Michael; Delgado-Olguin, Paul. (2017) Ehmt2/G9a controls the transition from development to maturation of the placental vasculature by activating the Notch Pathway. Development. 144:1976-1987.

28. Rahman, Anum; Zhou, Yu-Qing; Yee, Yohan; Dazai, Jun; Cahill, Lindsay S.; Kingdom, John; Macgowan, Chris; Sled, John G. (2017) Ultrasound detection of altered placental vascular morphology based on hemodynamic pulse wave reflection. American Journal of Physiology - Heart and Circulatory Physiology. 312:H1021-H1029.

27. Cahill, Lindsay S.; Bishop, Jonathan; Gazdzinski, Lisa M.; Dorr, Adrienne; Stefanovic, Bojana; Sled, John G. (2017) Altered cerebral blood flow and cerebrovascular function after voluntary exercise in adult mice. Brain Structure and Function. 222:3395-3405.

26. Dorr, Adrienne; Thomason, Lynsie A.; Koletar, Margaret M.; Joo, Illsung L.; Steinman, Joe; Cahill, Lindsay S.; Sled, John G.; Stefanovic, Bojana. (2017) Effects of voluntary exercise on structure and function of cortical microvasculature. Journal of Cerebral Blood Flow and Metabolism. 37:1046-1059.

25. Cahill, Lindsay S.; Gazdzinski, Lisa M.; Tsui, Albert K.Y.; Zhou, Yu-Qing; Portnoy, Sharon; Liu, Elaine; Mazer, C. David; Hare, Gregory M.T.; Kassner, Andrea; Sled, John G. (2017) Functional and anatomical evidence of cerebral tissue hypoxia in young sickle cell anemia mice. Journal of Cerebral Blood Flow and Metabolism. 37:994-1005.

24. McDonald, Chloë R.; Cahill, Lindsay S.; Ho, Keith T.; Yang, Jimmy; Kim, Hani; Silver, Karlee L.; Ward, Peter A.; Mount, Howard T.; Liles, W. Conrad; Sled, John G.; Kain, Kevin C. (2015) Experimental malaria in pregnancy induces neurocognitive injury in uninfected offspring via a C5a-C5a receptor dependent pathway. PLoS Pathogens. 11:e1005140.

23. Cahill, Lindsay S.; Steadman, Patrick E.; Jones, Carly E.; Laliberté, Christine L.; Dazai, Jun; Lerch, Jason P.; Stefanovic, Bojana; Sled, John G. (2015) MRI-detectable changes in mouse brain structure induced by voluntary exercise. NeuroImage. 113:175-183. 

22. Macgowan, Christopher K.; Stoops, Sarah Joy; Zhou, Yu-Qing; Cahill, Lindsay S.; Sled, John G. (2015) Evaluation of cerebrovascular impedance and wave reflection in the mouse by ultrasound. Journal of Cerebral Blood Flow and Metabolism. 35:521-526.

21. Allemang-Grand, Rylan; Scholz, Jan D.; Ellegood, Jacob; Cahill, Lindsay S.; Laliberté, Christine L.; Fraser, Paul E.; Josselyn, Sheena, A.; Sled, John G.; Lerch, Jason P. (2015) Altered brain development in an early-onset murine model of Alzheimer’s disease. Neurobiology of Aging. 36:638-647.

20. Cahill, Lindsay S.; Laliberté, Christine L.; Liu, Xue Jun; Bishop, Jonathan; Nieman, Brian J.; Mogil, Jeffrey S.; Sorge, Robert E.; Jones, Catherine D.; Salter, Michael W.; Henkelman, R. Mark (2014) Quantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse. Molecular Pain. 10:60.

19. Zhou, Yu-Qing; Cahill, Lindsay S.; Wong, Michael D.; Seed, Mike; Macgowan, Christopher K.; Sled, John G. (2014) Assessment of flow distribution in the mouse fetal circulation at late gestation using high frequency Doppler ultrasound. Physiological Genomics. 46:602-614.

18. Tsui, Albert K.Y.; Marsden, Philip A.; Mazer, C. David; Sled, John G.; Lee, Keith M.; Henkelman, R. Mark; Cahill, Lindsay S.; Zhou, Yu-Qing; Chan, Neville; Liu, Elaine; Hare, Gregory M.T. (2014) Differential HIF and NOS Responses to Acute Anemia: Defining Organ Specific Hemoglobin Thresholds for Tissue Hypoxia. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. 307:R13-R25.

17. Cahill, Lindsay S.; Zhou, Yu-Qing; Seed, Mike; Macgowan, Christopher K.; Sled, John G. (2014) Brain Sparing in Fetal Mice: BOLD MRI and Doppler Ultrasound Demonstrate Blood Redistribution During Hypoxia.  Journal of Cerebral Blood Flow and Metabolism.  34:1082-1088.

16. Paltser, Geoffrey; Liu, Xue Jun; Yantha, Jason; Winer, Shawn; Tsui, Hubert; Wu, Ping; Maezawa, Yuko; Cahill, Lindsay S.; Laliberté, Christine L.; Ramagopalan, Sreeram V.; DeLuca, Gabriele C.; Sadovnick, A. Dessa; Astsaturov, Igor; Ebers, George C.; Henkelman, R. Mark; Salter, Michael W.; Dosch, H-Michael (2013) TRPV1 Gates Tissue Access and Sustains Pathogenicity in Autoimmune Encephalitis. Molecular Medicine. 19:149-159.

15. Cahill, Lindsay S.; Laliberte, Christine L.; Ellegood, Jacob; Spring, Shoshana; Gleave, Jacqueline A.; van Eede, Matthijs C.; Lerch, Jason P.; Henkelman, R. Mark (2012) Preparation of Fixed Mouse Brains for MRI. NeuroImage. 60: 933-939.

14. Dazai, Jun; Spring, Shoshana; Cahill, Lindsay S.; Henkelman, R. Mark (2011) Multiple-Mouse Neuroanatomical Magnetic Resonance Imaging.  Journal of Visualized Experiments. 48:e2497.